BDBM50161888 4-[(2-Methoxy-ethyl)-methyl-amino]-but-2-enoic acid [4-(4-benzyloxy-3-chloro-phenylamino)-3-cyano-7-ethoxy-quinolin-6-yl]-amide::CHEMBL178144

SMILES CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ccccc4)c(Cl)c3)c2cc1NC(=O)\C=C\CN(C)CCOC

InChI Key InChIKey=LPYSKYXLEUHMAA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50161888   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50161888(4-[(2-Methoxy-ethyl)-methyl-amino]-but-2-enoic aci...)
Affinity DataIC50: 183nMAssay Description:Inhibition of human epidermal growth factor receptor-2 (HER-2) autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50161888(4-[(2-Methoxy-ethyl)-methyl-amino]-but-2-enoic aci...)
Affinity DataIC50: 68nMAssay Description:Inhibition of human epidermal growth factor receptor (EGFR) autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed