BDBM50161829 CHEMBL3794140

SMILES ONC(=O)[C@]1(F)[C@@H]([C@H]1c1ccc(cc1)-c1ncc(Cl)cn1)c1ccccc1

InChI Key InChIKey=PXXBZPNRBLVAQD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50161829   

TargetHistone deacetylase 4(Human)
Biofocus

Curated by ChEMBL
LigandPNGBDBM50161829(CHEMBL3794140)
Affinity DataIC50: 40nMAssay Description:Inhibition of HDAC4 catalytic domain (unknown origin) using Boc-Lys(TFA)-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2017
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Biofocus

Curated by ChEMBL
LigandPNGBDBM50161829(CHEMBL3794140)
Affinity DataIC50: 230nMAssay Description:Inhibition of HDAC4 in human Jurkat E6-1 cells using Lys-TFA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2017
Entry Details Article
PubMed