BDBM50161515 8-phenyl-1-(5-(pyridin-2-yl)-1,3,4-oxadiazol-2-yl)octan-1-one::CHEMBL182206

SMILES O=C(CCCCCCCc1ccccc1)c1nnc(o1)-c1ccccn1

InChI Key InChIKey=MKKVICQMAQSORB-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50161515   

TargetLiver carboxylesterase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50161515(8-phenyl-1-(5-(pyridin-2-yl)-1,3,4-oxadiazol-2-yl)...)
Affinity DataIC50: 200nMAssay Description:Inhibitory concentration of triacylgylcerol hydrolase using FP-Rh radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50161515(8-phenyl-1-(5-(pyridin-2-yl)-1,3,4-oxadiazol-2-yl)...)
Affinity DataIC50: 0.600nMAssay Description:Inhibitory concentration of fatty acid amide hydrolase using FP-Rh radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50161515(8-phenyl-1-(5-(pyridin-2-yl)-1,3,4-oxadiazol-2-yl)...)
Affinity DataKi:  3.20E+3nMAssay Description:Inhibitor affinity towards enzymes of class serine hydrolase was determined using biotin or fluorescent as radioligand (FP-biotin or FP-Rh)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50161515(8-phenyl-1-(5-(pyridin-2-yl)-1,3,4-oxadiazol-2-yl)...)
Affinity DataKi:  3.20E+3nMAssay Description:Inhibitor affinity towards enzymes of class serine hydrolase was determined using biotin or fluorescent as radioligand (FP-biotin or FP-Rh)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed