BDBM50161475 CHEMBL3785605

SMILES C(C1COc2ccccc2C1)N1CCC2(CCc3ccccc23)CC1

InChI Key InChIKey=SNUYVAGJPNKKOA-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50161475   

LigandPNGBDBM50161475(CHEMBL3785605)
Affinity DataIC50: 1.50E+3nMAssay Description:Displacement of [3H]dofetilide from human ERG channel expressed in HEK293 cells after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/5/2017
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50161475(CHEMBL3785605)
Affinity DataIC50: 122nMAssay Description:Antagonist activity at human NOP receptor expressed in HEK293 cells assessed as inhibition of N/OFQ-induced [35S]GTPgammaS binding after 1.5 hrs by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/5/2017
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50161475(CHEMBL3785605)
Affinity DataKi:  5.70nMAssay Description:Displacement of [3H]N/OFQ from human NOP receptor expressed in HEK293 cells after 45 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/5/2017
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50161475(CHEMBL3785605)
Affinity DataKi:  49nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHOK1 cells after 45 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/5/2017
Entry Details Article
PubMed