BDBM50161468 CHEMBL3794127

SMILES [#6]\[#6](-[#6])=[#6](\c1ccccc1)-c1ccc(\[#6]=[#6]\[#6](=O)-[#7]-[#8])cc1

InChI Key InChIKey=DBFKJLRDLFIBCM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50161468   

TargetHistone deacetylase 2(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50161468(CHEMBL3794127)
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of human recombinant HDAC2 using Fluor de Lys Green as substrate incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2017
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50161468(CHEMBL3794127)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of HDAC in human HeLa cells using BOC-Ac-Lys-AMC as substrate incubated for 4 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2017
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50161468(CHEMBL3794127)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of HDAC in human HeLa nuclear extract using BOC-Ac-Lys-AMC as substrate incubated for 90 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2017
Entry Details Article
PubMed