BDBM50161452 5-Fluoro-3-((S)-3-methyl-2-phenylcarbamoyloxy-butyrylamino)-4-oxo-pentanoic acid::CHEMBL180263

SMILES CC(C)[C@H](OC(=O)Nc1ccccc1)C(=O)NC(CC(O)=O)C(=O)CF

InChI Key InChIKey=VADGDBPFZAUONM-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50161452   

TargetCaspase-8(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161452(5-Fluoro-3-((S)-3-methyl-2-phenylcarbamoyloxy-buty...)
Affinity DataIC50: 17nMAssay Description:Inhibitory concentration against Caspase-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161452(5-Fluoro-3-((S)-3-methyl-2-phenylcarbamoyloxy-buty...)
Affinity DataIC50: 17nMAssay Description:Inhibitory concentration against human caspase-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-9(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161452(5-Fluoro-3-((S)-3-methyl-2-phenylcarbamoyloxy-buty...)
Affinity DataIC50: 30nMAssay Description:Inhibitory concentration against Caspase-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161452(5-Fluoro-3-((S)-3-methyl-2-phenylcarbamoyloxy-buty...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against Calpain 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-6(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161452(5-Fluoro-3-((S)-3-methyl-2-phenylcarbamoyloxy-buty...)
Affinity DataIC50: 50nMAssay Description:Inhibitory concentration against Caspase-6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161452(5-Fluoro-3-((S)-3-methyl-2-phenylcarbamoyloxy-buty...)
Affinity DataIC50: 11nMAssay Description:Inhibitory concentration against Caspase-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed