BDBM50161320 3,4-Dichloro-N-{[methyl-((S)-1-phenyl-2-pyrrolidin-1-yl-ethyl)-carbamoyl]-methyl}-benzamide::CHEMBL361199

SMILES CN([C@H](CN1CCCC1)c1ccccc1)C(=O)CNC(=O)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=NSWBJPTXKZWEHU-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50161320   

TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50161320(3,4-Dichloro-N-{[methyl-((S)-1-phenyl-2-pyrrolidin...)
Affinity DataEC50:  2.25nMAssay Description:In vitro effective concentration towards human kappa opioid receptor was determined using [35S]-GTP-gamma S as radioligand; Not determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50161320(3,4-Dichloro-N-{[methyl-((S)-1-phenyl-2-pyrrolidin...)
Affinity DataKi:  3.60nMAssay Description:In vitro binding affinity for human kappa opioid receptor was determined by using [3H]diprenorphine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed