BDBM50161315 CHEMBL179627::N-({[(S)-2-((R)-3-Hydroxy-pyrrolidin-1-yl)-1-phenyl-ethyl]-methyl-carbamoyl}-methyl)-2-methoxy-benzamide

SMILES COc1ccccc1C(=O)NCC(=O)N(C)[C@H](CN1CC[C@@H](O)C1)c1ccccc1

InChI Key InChIKey=PXPJOAVITOEIEW-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50161315   

TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50161315(N-({[(S)-2-((R)-3-Hydroxy-pyrrolidin-1-yl)-1-pheny...)
Affinity DataEC50:  1.98nMAssay Description:In vitro effective concentration towards human kappa opioid receptor was determined using [35S]-GTP-gamma S as radioligand; Not determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50161315(N-({[(S)-2-((R)-3-Hydroxy-pyrrolidin-1-yl)-1-pheny...)
Affinity DataKi:  2nMAssay Description:In vitro binding affinity for human kappa opioid receptor was determined by using [3H]diprenorphine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed