BDBM50160868 CHEMBL499504

SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)c1cccc2CCCCc12)B(O)O

InChI Key InChIKey=MZHTUAPXZCUHOQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50160868   

TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandPNGBDBM50160868(CHEMBL499504)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of chymotrypsin like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate preincubated for 10 mins followed by subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandPNGBDBM50160868(CHEMBL499504)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of chymotrypsin like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate preincubated for 10 mins followed by subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandPNGBDBM50160868(CHEMBL499504)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of chymotrypsin like activity of human erythrocyte-derived 20S proteasome preincubated for 10 mins using Suc-LLVY-AMC as substrate after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2017
Entry Details Article
PubMed