BDBM50160838 CHEMBL365198::N-Methyl-N-[(S)-1-(3-nitro-phenyl)-2-pyrrolidin-1-yl-ethyl]-2-(4-trifluoromethyl-phenyl)-acetamide

SMILES CN([C@H](CN1CCCC1)c1cccc(c1)[N+]([O-])=O)C(=O)Cc1ccc(cc1)C(F)(F)F

InChI Key InChIKey=LOWHYEVMLNYNLM-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50160838   

TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50160838(N-Methyl-N-[(S)-1-(3-nitro-phenyl)-2-pyrrolidin-1-...)
Affinity DataKi:  0.630nMAssay Description:Displacement of bound [3H]diprenorphine from membranes expressing cloned human kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed