BDBM50160602 5-Fluoro-3-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-cyclohexyl}-1H-indole::CHEMBL181784

SMILES COc1ccccc1N1CCN(CC1)[C@H]1CC[C@H](CC1)c1c[nH]c2ccc(F)cc12

InChI Key InChIKey=PXPDZPCPTSKVAX-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50160602   

TargetSodium-dependent serotonin transporter(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50160602(5-Fluoro-3-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl...)
Affinity DataKi:  3.30nMAssay Description:Binding affinity determined against Serotonin transporter determined by displacement of [3H]paroxetine from rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50160602(5-Fluoro-3-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl...)
Affinity DataKi:  129nMAssay Description:Binding affinity determined against human 5-hydroxytryptamine 1A receptors transfected into CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed