BDBM50160417 (S)-[(S)-7-Iodo-2,5-dioxo-3-(4-trifluoromethyl-phenyl)-1,2,3,5-tetrahydro-benzo[e][1,4]diazepin-4-yl]-phenyl-acetic acid::CHEMBL178578::[(S)-7-Iodo-2,5-dioxo-3-((S)-4-trifluoromethyl-phenyl)-1,2,3,5-tetrahydro-benzo[e][1,4]diazepin-4-yl]-phenyl-acetic acid

SMILES OC(=O)[C@@H](N1[C@@H](c2ccc(cc2)C(F)(F)F)C(=O)Nc2ccc(I)cc2C1=O)c1ccccc1

InChI Key InChIKey=OUJPKXOGQQVHGA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50160417   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50160417([(S)-7-Iodo-2,5-dioxo-3-((S)-4-trifluoromethyl-phe...)
Affinity DataIC50: 1.70E+3nMAssay Description:Binding affinity between MDM2 and p53 protein in fluorescence peptide assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed