BDBM50160283 CHEMBL3787346

SMILES Fc1ccc(cc1)[C@H]1[C@@H](N(C2CCN(CC2)C(=O)n2cncn2)C1=O)c1ccc2OCOc2c1

InChI Key InChIKey=XRIROGBLGLPXQI-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50160283   

TargetFatty-acid amide hydrolase 1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50160283(CHEMBL3787346)
Affinity DataIC50: 7.74E+3nMAssay Description:Inhibition of recombinant C-terminal His-tagged human FAAH expressed in sf21 cells using N-arachidonoyl-[14C]-ethanolamine as substrate assessed as r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2017
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50160283(CHEMBL3787346)
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant C-terminal His6-tagged human MAGL expressed in Escherichia coli using 2-arachidonoyl-[3H]-glycerol as substrate incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2017
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50160283(CHEMBL3787346)
Affinity DataIC50: 729nMAssay Description:Inhibition of recombinant C-terminal His6-tagged human MAGL expressed in Escherichia coli using 2-arachidonoyl-[3H]-glycerol as substrate preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2017
Entry Details Article
PubMed
TargetMonoglyceride lipase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50160283(CHEMBL3787346)
Affinity DataIC50: 0.0700nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMonoglyceride lipase(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50160283(CHEMBL3787346)
Affinity DataIC50: 0.0860nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50160283(CHEMBL3787346)
Affinity DataIC50: 0.0780nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed