BDBM50159695 CHEMBL3787617

SMILES CN1c2ccc(cc2CC[C@H](NC(=O)c2cc(Cc3ccccc3)on2)C1=O)C1(N=N1)C(F)(F)F

InChI Key InChIKey=SIDIZJFULUPVLJ-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50159695   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50159695(CHEMBL3787617)Copy SMILESCopy InChI

Affinity DataIC50: 210nMAssay Description:Binding affinity to Flag-tagged human RIP1 (1 to 324 residues) at 10 uM after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/23/2017
Entry Details Article
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