BDBM50159544 CHEMBL3787103

SMILES CCn1cc(Nc2nc(Nc3cc(C)c(cc3OC(C)C)C3CCNCC3)ncc2Cl)c(n1)S(=O)(=O)C(C)C

InChI Key InChIKey=NNNQIXXZLQIIFE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50159544   

TargetALK tyrosine kinase receptor(Human)
Beijing Pearl Biotech

Curated by ChEMBL
LigandPNGBDBM50159544(CHEMBL3787103)
Affinity DataIC50: 28nMAssay Description:Inhibition of recombinant human ALK L1196M mutant using tyrosine kinase substrate-biotin after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2017
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Beijing Pearl Biotech

Curated by ChEMBL
LigandPNGBDBM50159544(CHEMBL3787103)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human wild type ALK using tyrosine kinase substrate-biotin after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2017
Entry Details Article
PubMed