BDBM50159540 CHEMBL3785304

SMILES CC(C)S(=O)(=O)c1nn(C)cc1Nc1ncnc(Nc2cc(C)c(cc2OC2CC2)C2CCN(C)CC2)n1

InChI Key InChIKey=QZTJFPNDINUDKF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50159540   

TargetALK tyrosine kinase receptor(Human)
Beijing Pearl Biotech

Curated by ChEMBL
LigandPNGBDBM50159540(CHEMBL3785304)
Affinity DataIC50: 36nMAssay Description:Inhibition of recombinant human wild type ALK using tyrosine kinase substrate-biotin after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2017
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Beijing Pearl Biotech

Curated by ChEMBL
LigandPNGBDBM50159540(CHEMBL3785304)
Affinity DataIC50: 111nMAssay Description:Inhibition of recombinant human ALK L1196M mutant using tyrosine kinase substrate-biotin after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2017
Entry Details Article
PubMed