BDBM50159521 CHEMBL3785232

SMILES CCC(C)S(=O)(=O)c1nn(C)cc1Nc1nc(Nc2cc(C)c(cc2OC(C)C)C2CCNCC2)ncc1Cl

InChI Key InChIKey=XSVGIEWPPRGQHN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50159521   

TargetALK tyrosine kinase receptor(Human)
Beijing Pearl Biotech

Curated by ChEMBL
LigandPNGBDBM50159521(CHEMBL3785232)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human ALK L1196M mutant using tyrosine kinase substrate-biotin after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2017
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Beijing Pearl Biotech

Curated by ChEMBL
LigandPNGBDBM50159521(CHEMBL3785232)
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human wild type ALK using tyrosine kinase substrate-biotin after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2017
Entry Details Article
PubMed