BDBM50159505 CHEMBL1779158::N,N-Dibenzyltryptamine

SMILES C(Cc1c[nH]c2ccccc12)N(Cc1ccccc1)Cc1ccccc1

InChI Key InChIKey=WEWPMAKQEUSKPV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50159505   

LigandPNGBDBM50159505(N,N-Dibenzyltryptamine | CHEMBL1779158)
Affinity DataIC50: 367nMAssay Description:Antagonist activity at rat TRPM8 expressed in HEK293 cells assessed as inhibition of menthol mediated current amplitude at +80 mV holding potential b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2017
Entry Details Article
PubMed
LigandPNGBDBM50159505(N,N-Dibenzyltryptamine | CHEMBL1779158)
Affinity DataIC50: 3.20E+3nMAssay Description:Antagonist activity at rat TRPM8 expressed in HEK293 cells assessed as reduction in menthol-induced calcium flux incubated for 60 mins by Fluo-4 NW-d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50159505(N,N-Dibenzyltryptamine | CHEMBL1779158)
Affinity DataIC50: 35nMAssay Description:Modulation of TRPV1 (unknown origin) by fluorometric imaging plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetTransient receptor potential cation channel subfamily M member 8(Human)
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50159505(N,N-Dibenzyltryptamine | CHEMBL1779158)
Affinity DataIC50: 800nMAssay Description:Antagonist activity at TRPM8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed