BDBM50159455 CHEMBL262258::cyclo(7-12) Des-AA1,2,5-[Glu7,D-Trp8,(NMe)IAmp9,m-I-Tyr11,hhLys12]SRIF

SMILES CC(C)NCc1ccc(C[C@@H]2N(C)C(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCCCCC[C@H](NC(=O)[C@H](Cc4ccc(O)cc4I)NC(=O)[C@H](NC2=O)[C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CSSC[C@@H](N)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)C(N)=O)cc1

InChI Key InChIKey=JYOCNGWPKKTNFK-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50159455   

TargetSomatostatin receptor type 4(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50159455(cyclo(7-12) Des-AA1,2,5-[Glu7,D-Trp8,(NMe)IAmp9,m-...)
Affinity DataIC50: 611nMAssay Description:Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 1(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50159455(cyclo(7-12) Des-AA1,2,5-[Glu7,D-Trp8,(NMe)IAmp9,m-...)
Affinity DataIC50: 46nMAssay Description:Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50159455(cyclo(7-12) Des-AA1,2,5-[Glu7,D-Trp8,(NMe)IAmp9,m-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 3(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50159455(cyclo(7-12) Des-AA1,2,5-[Glu7,D-Trp8,(NMe)IAmp9,m-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50159455(cyclo(7-12) Des-AA1,2,5-[Glu7,D-Trp8,(NMe)IAmp9,m-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed