BDBM50159433 CHEMBL409120::cyclo(7-12) Des-AA1,5-[Tyr2,Glu7,D-Trp8,IAmp9,D-hhLys12]SRIF

SMILES CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCCCCC[C@@H](NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@H](NC2=O)[C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)C(O)=O)cc1

InChI Key InChIKey=PWNGKIWHLMJETN-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50159433   

TargetSomatostatin receptor type 3(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50159433(cyclo(7-12) Des-AA1,5-[Tyr2,Glu7,D-Trp8,IAmp9,D-hh...)
Affinity DataIC50: 772nMAssay Description:Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50159433(cyclo(7-12) Des-AA1,5-[Tyr2,Glu7,D-Trp8,IAmp9,D-hh...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 1(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50159433(cyclo(7-12) Des-AA1,5-[Tyr2,Glu7,D-Trp8,IAmp9,D-hh...)
Affinity DataIC50: 204nMAssay Description:Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50159433(cyclo(7-12) Des-AA1,5-[Tyr2,Glu7,D-Trp8,IAmp9,D-hh...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 4(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50159433(cyclo(7-12) Des-AA1,5-[Tyr2,Glu7,D-Trp8,IAmp9,D-hh...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed