BDBM50159367 (2S,4R)-4-Benzoylsulfanyl-2-(2,4,5-trifluoro-benzyloxymethyl)-pyrrolidine-1-carboxylic acid 2,3-dihydro-benzo[1,4]dioxin-5-yl ester::CHEMBL193490

SMILES Fc1cc(F)c(COC[C@@H]2C[C@H](CN2C(=O)Oc2cccc3OCCOc23)SC(=O)c2ccccc2)cc1F

InChI Key InChIKey=UZHWIRWAHWQBBD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50159367   

TargetEndothelin-converting enzyme 1(Human)
University Institute of Pathology

Curated by ChEMBL
LigandPNGBDBM50159367((2S,4R)-4-Benzoylsulfanyl-2-(2,4,5-trifluoro-benzy...)
Affinity DataIC50: 49.7nMAssay Description:Inhibitory concentration against human ECE-1 by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetNeprilysin(Human)
University Institute of Pathology

Curated by ChEMBL
LigandPNGBDBM50159367((2S,4R)-4-Benzoylsulfanyl-2-(2,4,5-trifluoro-benzy...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against NeprilysinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
University Institute of Pathology

Curated by ChEMBL
LigandPNGBDBM50159367((2S,4R)-4-Benzoylsulfanyl-2-(2,4,5-trifluoro-benzy...)
Affinity DataIC50: 481nMAssay Description:Inhibitory concentration against human ECE-1 expressed in MDCK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Human)
University Institute of Pathology

Curated by ChEMBL
LigandPNGBDBM50159367((2S,4R)-4-Benzoylsulfanyl-2-(2,4,5-trifluoro-benzy...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against human angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed