BDBM50159340 CHEMBL3786169

SMILES COc1ccc(cc1)-c1nnc(o1)C(=O)N1CC(C1)Oc1ccc(CN2CCCC2)cc1

InChI Key InChIKey=WYFUMSGPZNMEEQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50159340   

TargetMelanin-concentrating hormone receptor 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50159340(CHEMBL3786169)
Affinity DataIC50: 34nMAssay Description:Antagonist activity at human MCHR1 expressed in CHO cell membranes preincubated for 5 mins followed by addition of MCH peptide measured after 45 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2017
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Mouse)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50159340(CHEMBL3786169)
Affinity DataIC50: 6nMAssay Description:Displacement of [125I]Tyr13-MCH from mouse MCHR1 after 60 mins by microbeta scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2017
Entry Details Article
PubMed
LigandPNGBDBM50159340(CHEMBL3786169)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of human ERG by IonWork assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2017
Entry Details Article
PubMed