BDBM50159267 2-(4-methylphenyl)ethylamine::2-p-Tolyl-ethylamine::CHEMBL103299

SMILES Cc1ccc(CCN)cc1

InChI Key InChIKey=VKJXAQYPOTYDLO-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50159267   

TargetCytochrome P450 2A6(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50159267(2-p-Tolyl-ethylamine | 2-(4-methylphenyl)ethylamin...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibitory concentration against human cytochrome P450 2A6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50159267(2-p-Tolyl-ethylamine | 2-(4-methylphenyl)ethylamin...)
Affinity DataEC50:  4.38E+3nMAssay Description:Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2A5(Mouse)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50159267(2-p-Tolyl-ethylamine | 2-(4-methylphenyl)ethylamin...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory concentration against mouse cytochrome P450 2A5More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50159267(2-p-Tolyl-ethylamine | 2-(4-methylphenyl)ethylamin...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibitory concentration against recombinant human cytochrome P450 1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50159267(2-p-Tolyl-ethylamine | 2-(4-methylphenyl)ethylamin...)
Affinity DataIC50: 77nMAssay Description:Inhibition of SARS-Cov-2 main protease using fluorogenic substrate [5-FAM]-AVLQSGFR-[Lys(Dabcyl)]-K-amide by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed