BDBM501592 US11026958, Example 11::US11026958, Example C5

SMILES NS(=O)(=O)c1ccc(cc1)C1CC1c1nccc(n1)-c1cncc(c1)C(F)(F)F

InChI Key InChIKey=OAYPKNFMCNKEPZ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 501592   

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM501592(US11026958, Example C5 | US11026958, Example 11)
Affinity DataEC50:  240nMAssay Description:Test compounds were serially diluted in DMSO and then resuspended to the final test concentration in external recording solution, with, or without 40...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM501592(US11026958, Example C5 | US11026958, Example 11)
Affinity DataEC50:  3.30E+3nMAssay Description:Test compounds were serially diluted in DMSO and then resuspended to the final test concentration in external recording solution, with, or without 40...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent