BDBM50159062 CHEMBL3786031

SMILES CCc1c(c([nH]c1C(=O)Nc2cc(ccc2O)S(=O)(=O)N(CC)CC)C)C(=O)CO

InChI Key InChIKey=ZRRMTUAVTCNCOA-UHFFFAOYSA-N

Data  3 Kd

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50159062   

TargetBromodomain-containing protein 4(Human)
Albert-Ludwigs-University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50159062(CHEMBL3786031)
Affinity DataKd:  7.90E+3nMAssay Description:Binding affinity to partial length human BRD4 bromodomain 1 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2017
Entry Details Article
PubMed
TargetBromodomain-containing protein 3(Human)
Albert-Ludwigs-University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50159062(CHEMBL3786031)
Affinity DataKd:  4.90E+3nMAssay Description:Binding affinity to partial length human BRD3 bromodomain 1 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2017
Entry Details Article
PubMed
TargetBromodomain-containing protein 3(Human)
Albert-Ludwigs-University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50159062(CHEMBL3786031)
Affinity DataKd:  1.10E+4nMAssay Description:Binding affinity to partial length human BRD3 bromodomain 2 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2017
Entry Details Article
PubMed