BDBM50158921 5-Pyridin-3-yl-furan-2-carbaldehyde oxime::5-Pyridin-3-yl-furan-2-carbaldehyde oxime; compound with 5-pyridin-3-yl-furan-2-carbaldehyde oxime::CHEMBL178330::CHEMBL178547::CHEMBL1795039::US8609708, 24::US8609708, 39::US8609708, 72

SMILES O=NCc1ccc(o1)-c1cccnc1

InChI Key InChIKey=OIFZZHGYNVANQJ-UHFFFAOYSA-N

Data  2 KI  27 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 29 hits for monomerid = 50158921   

TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

US Patent
LigandPNGBDBM50158921(US8609708, 24 | CHEMBL178330 | CHEMBL178547 | CHEM...)
Affinity DataIC50: 9.75E+3nMAssay Description:The inhibition of human CYP2A6-mediated 7-hydroxy coumarin formation was evaluated in the presence of 95 selected test compounds in a standard assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2014
Entry Details
Go to US Patent

TargetCytochrome P450 2B6(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50158921(US8609708, 24 | CHEMBL178330 | CHEMBL178547 | CHEM...)
Affinity DataIC50: 2.06E+5nMAssay Description:Inhibitory concentration value against human cytochrome P-450 2B6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50158921(US8609708, 24 | CHEMBL178330 | CHEMBL178547 | CHEM...)
Affinity DataIC50: 8.62E+4nMAssay Description:Inhibitory concentration against human cytochrome P-450 2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2E1(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50158921(US8609708, 24 | CHEMBL178330 | CHEMBL178547 | CHEM...)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibitory concentration value against human cytochrome P-450 2E1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50158921(US8609708, 24 | CHEMBL178330 | CHEMBL178547 | CHEM...)
Affinity DataIC50: 1.75E+5nMAssay Description:Inhibitory concentration value against human cytochrome P-450 2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50158921(US8609708, 24 | CHEMBL178330 | CHEMBL178547 | CHEM...)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibitory concentration value against human cytochrome P-450 3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50158921(US8609708, 24 | CHEMBL178330 | CHEMBL178547 | CHEM...)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibitory concentration value against human cytochrome P-450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

US Patent
LigandPNGBDBM50158921(US8609708, 24 | CHEMBL178330 | CHEMBL178547 | CHEM...)
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibitory concentration value against human cytochrome P-450 2A6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50158921(US8609708, 24 | CHEMBL178330 | CHEMBL178547 | CHEM...)
Affinity DataIC50: 5.19E+4nMAssay Description:Inhibitory concentration value against human cytochrome P-450 3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

US Patent
LigandPNGBDBM50158921(US8609708, 24 | CHEMBL178330 | CHEMBL178547 | CHEM...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibitory concentration value against human cytochrome P-450 2A6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

US Patent
LigandPNGBDBM50158921(US8609708, 24 | CHEMBL178330 | CHEMBL178547 | CHEM...)
Affinity DataIC50: 8.23E+4nMAssay Description:Inhibitory concentration value against human cytochrome P-450 2A6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50158921(US8609708, 24 | CHEMBL178330 | CHEMBL178547 | CHEM...)
Affinity DataIC50: 2.79E+5nMAssay Description:Inhibitory concentration value against human cytochrome P-450 2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50158921(US8609708, 24 | CHEMBL178330 | CHEMBL178547 | CHEM...)
Affinity DataIC50: 1.18E+5nMAssay Description:Inhibitory concentration value against human cytochrome P-450 2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2E1(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50158921(US8609708, 24 | CHEMBL178330 | CHEMBL178547 | CHEM...)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibitory concentration value against human cytochrome P-450 2E1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50158921(US8609708, 24 | CHEMBL178330 | CHEMBL178547 | CHEM...)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibitory concentration value against human cytochrome P-450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50158921(US8609708, 24 | CHEMBL178330 | CHEMBL178547 | CHEM...)
Affinity DataIC50: 1.41E+5nMAssay Description:Inhibitory concentration against human cytochrome P-450 2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50158921(US8609708, 24 | CHEMBL178330 | CHEMBL178547 | CHEM...)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibitory concentration value against human cytochrome P-450 3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50158921(US8609708, 24 | CHEMBL178330 | CHEMBL178547 | CHEM...)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibitory concentration value against human cytochrome P-450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50158921(US8609708, 24 | CHEMBL178330 | CHEMBL178547 | CHEM...)
Affinity DataIC50: 3.98E+5nMAssay Description:Inhibitory concentration against human cytochrome P-450 2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2E1(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50158921(US8609708, 24 | CHEMBL178330 | CHEMBL178547 | CHEM...)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibitory concentration value against human cytochrome P-450 2E1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2B6(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50158921(US8609708, 24 | CHEMBL178330 | CHEMBL178547 | CHEM...)
Affinity DataIC50: 3.72E+5nMAssay Description:Inhibitory concentration value against human cytochrome P-450 2B6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2B6(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50158921(US8609708, 24 | CHEMBL178330 | CHEMBL178547 | CHEM...)
Affinity DataIC50: 1.28E+5nMAssay Description:Inhibitory concentration value against human cytochrome P-450 2B6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50158921(US8609708, 24 | CHEMBL178330 | CHEMBL178547 | CHEM...)
Affinity DataIC50: 4.00E+5nMAssay Description:To gain insight into the selectivity of the synthetic compounds, nicotine, nicotine related alkaloids and nicotine metabolites for inhibition of othe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2014
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50158921(US8609708, 24 | CHEMBL178330 | CHEMBL178547 | CHEM...)
Affinity DataIC50: 4.00E+5nMAssay Description:To gain insight into the selectivity of the synthetic compounds, nicotine, nicotine related alkaloids and nicotine metabolites for inhibition of othe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2014
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50158921(US8609708, 24 | CHEMBL178330 | CHEMBL178547 | CHEM...)
Affinity DataIC50: 4.00E+5nMAssay Description:To gain insight into the selectivity of the synthetic compounds, nicotine, nicotine related alkaloids and nicotine metabolites for inhibition of othe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2014
Entry Details
Go to US Patent

TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

US Patent
LigandPNGBDBM50158921(US8609708, 24 | CHEMBL178330 | CHEMBL178547 | CHEM...)
Affinity DataIC50: 8.23E+4nMAssay Description:The inhibition of human CYP2A6-mediated 7-hydroxy coumarin formation was evaluated in the presence of 95 selected test compounds in a standard assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2014
Entry Details
Go to US Patent

TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

US Patent
LigandPNGBDBM50158921(US8609708, 24 | CHEMBL178330 | CHEMBL178547 | CHEM...)
Affinity DataIC50: 4.24E+3nMAssay Description:The inhibition of human CYP2A6-mediated 7-hydroxy coumarin formation was evaluated in the presence of 95 selected test compounds in a standard assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2014
Entry Details
Go to US Patent

TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

US Patent
LigandPNGBDBM50158921(US8609708, 24 | CHEMBL178330 | CHEMBL178547 | CHEM...)
Affinity DataKi:  710nMAssay Description:Effect on coumarin 7-hydroxylation by human Cytochrome P-450 2A6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

US Patent
LigandPNGBDBM50158921(US8609708, 24 | CHEMBL178330 | CHEMBL178547 | CHEM...)
Affinity DataKi:  1.37E+4nMAssay Description:Effect on coumarin 7-hydroxylation by human Cytochrome P-450 2A6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed