BDBM50158909 CHEMBL3787231

SMILES CCc1c(c([nH]c1C(=O)Nc2cc(ccc2O)S(=O)(=O)N(CC)CC)C)C(=O)C

InChI Key InChIKey=DPBKLIVPNYGQQG-UHFFFAOYSA-N

Data  9 Kd

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50158909   

TargetBromodomain-containing protein 4(Human)
Albert-Ludwigs-University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50158909(CHEMBL3787231)
Affinity DataKd:  240nMAssay Description:Binding affinity to partial length human BRD4 bromodomain 1 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2017
Entry Details Article
PubMed
TargetBromodomain-containing protein 3(Human)
Albert-Ludwigs-University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50158909(CHEMBL3787231)
Affinity DataKd:  2.90E+3nMAssay Description:Binding affinity to partial length human BRD3 bromodomain 1 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2017
Entry Details Article
PubMed
TargetBromodomain-containing protein 3(Human)
Albert-Ludwigs-University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50158909(CHEMBL3787231)
Affinity DataKd:  2.40E+3nMAssay Description:Binding affinity to partial length human BRD3 bromodomain 2 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2017
Entry Details Article
PubMed
TargetPeregrin(Human)
Albert-Ludwigs-University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50158909(CHEMBL3787231)
Affinity DataKd:  3.80E+4nMAssay Description:Binding affinity to partial length human BRPF1 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2017
Entry Details Article
PubMed
TargetBromodomain-containing protein 3(Human)
Albert-Ludwigs-University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50158909(CHEMBL3787231)
Affinity DataKd:  380nMAssay Description:Binding affinity to human BRD3 domain 1 assessed as dissociation constant by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50158909(CHEMBL3787231)
Affinity DataKd:  830nMAssay Description:Binding affinity to human BRD2 domain 2 assessed as dissociation constant by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50158909(CHEMBL3787231)
Affinity DataKd:  170nMAssay Description:Binding affinity to human BRD2 domain 1 assessed as dissociation constant by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Albert-Ludwigs-University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50158909(CHEMBL3787231)
Affinity DataKd:  160nMAssay Description:Binding affinity to human BRD4 domain 1 (unknown origin) assessed as dissociation constant by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBromodomain-containing protein 3(Human)
Albert-Ludwigs-University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50158909(CHEMBL3787231)
Affinity DataKd:  490nMAssay Description:Binding affinity to human BRD3 domain 2 assessed as dissociation constant by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed