BDBM50158860 CHEMBL3785378

SMILES CCN1CCC[C@H](CNCc2cc(ccn2)C(O)=O)C1=O

InChI Key InChIKey=SESICOAOPDFZFN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50158860   

TargetLysine-specific demethylase 2B(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50158860(CHEMBL3785378)
Affinity DataIC50: 250nMAssay Description:Inhibition of recombinant human C-terminal FLAG-tagged KDM2B (1 to 650 residues) expressed in baculovirus infected sf9 cells using biotin-H3K36me2 as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2017
Entry Details Article
PubMed
TargetLysine-specific demethylase 5B(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50158860(CHEMBL3785378)
Affinity DataIC50: 250nMAssay Description:Inhibition of KDM5B (1 to 809 residues) (unknown origin) expressed in Escherichia coli using biotin-H3K4me3 as substrate preincubated for 10 mins fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2017
Entry Details Article
PubMed
TargetLysine-specific demethylase 6A(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50158860(CHEMBL3785378)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of KDM6A (919 to 1401 residues) (unknown origin) expressed in Escherichia coli using biotinylated histone H3 as substrate preincubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2017
Entry Details Article
PubMed