BDBM50158586 CHEMBL3785668

SMILES Cc1nnc(C[C@@H]2C=C(c3ccc(Cl)cc3)c3ccccc3-n3c(C)nnc23)o1

InChI Key InChIKey=AGYIAWHWIUZNSD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50158586   

TargetBromodomain-containing protein 4(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50158586(CHEMBL3785668)
Affinity DataIC50: 20nMAssay Description:Displacement of biotinylated tetra-acetylated histone H4 from his-tagged BRD4 bromodomain1 (unknown origin) incubated for 1 hr at 22 degC followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed