BDBM50158510 CHEMBL1369708

SMILES NS(=O)(=O)c1ccc(cc1)N=C1C(=O)Nc2ccccc12

InChI Key InChIKey=FXNKQWYBLXKGFU-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50158510   

TargetCarbonic anhydrase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50158510(CHEMBL1369708)
Affinity DataKi:  3nMAssay Description:Binding affinity to human recombinant CA2 assessed as inhibition constant incubated for 15 mins prior to testing by phenol red based stopped-flow CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCarbonic anhydrase 9(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50158510(CHEMBL1369708)
Affinity DataKi:  14nMAssay Description:Binding affinity to human recombinant CA9 assessed as inhibition constant incubated for 15 mins prior to testing by phenol red based stopped-flow CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCarbonic anhydrase 12(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50158510(CHEMBL1369708)
Affinity DataKi:  34nMAssay Description:Binding affinity to human recombinant CA12 assessed as inhibition constant incubated for 15 mins prior to testing by phenol red based stopped-flow CO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCarbonic anhydrase(Yeast)
Bezmialem Vakif University

Curated by ChEMBL
LigandPNGBDBM50158510(CHEMBL1369708)
Affinity DataKi:  48nMAssay Description:Inhibition of recombinant Candida glabrata beta carbonic anhydrase NCE103 expressed in Escherichia coli preincubated for 15 mins by stopped-flow CO2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase(Yeast)
Bezmialem Vakif University

Curated by ChEMBL
LigandPNGBDBM50158510(CHEMBL1369708)
Affinity DataKi:  87nMAssay Description:Inhibition of recombinant Candida albicans beta carbonic anhydrase NCE103 expressed in Escherichia coli preincubated for 15 mins by stopped-flow CO2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Bezmialem Vakif University

Curated by ChEMBL
LigandPNGBDBM50158510(CHEMBL1369708)
Affinity DataKi:  422nMAssay Description:Inhibition of recombinant human carbonic anhydrase 1 expressed in Escherichia coli preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50158510(CHEMBL1369708)
Affinity DataKi:  523nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 expressed in Escherichia coli preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2017
Entry Details Article
PubMed