BDBM50158486 (1R,3S,5Z)-5-{2-[(1R,3aS,4E,7aR)-1-[(2R)-4-(benzenesulfonyl)butan-2-yl]-7a-methyl-octahydro-1H-inden-4-ylidene]ethylidene}-4-methylidenecyclohexane-1,3-diol::CHEMBL224719

SMILES C[C@H](CCS(=O)(=O)c1ccccc1)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C

InChI Key InChIKey=FWJLSQNOVVHPLP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50158486   

Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Human)
The Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50158486((1R,3S,5Z)-5-{2-[(1R,3aS,4E,7aR)-1-[(2R)-4-(benzen...)
Affinity DataIC50: 28nMAssay Description:Inhibition of human CYP24 hydroxylase expressed in V79 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Human)
The Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50158486((1R,3S,5Z)-5-{2-[(1R,3aS,4E,7aR)-1-[(2R)-4-(benzen...)
Affinity DataIC50: 28nMAssay Description:Inhibition of human CYP24A1 expressed in Chinese hamster V79 cells using [3H-1beta]-1alpha,25(OH)2D3 as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed