BDBM50158484 (R)-3-amino-N-(3-(2,4-dichlorophenyl)-1-oxo-1-(4-(2-((2-(thiophen-2-yl)ethylamino)methyl)phenyl)piperazin-1-yl)propan-2-yl)propanamide::3-Amino-N-[(R)-1-(2,4-dichloro-benzyl)-2-oxo-2-(4-{2-[(2-thiophen-2-yl-ethylamino)-methyl]-phenyl}-piperazin-1-yl)-ethyl]-propionamide::4-(2R)-[3-aminopropionylamido]-3-(2,4-dichlorophenyl)propionyl-1-2-[(thienyl)ethylaminomethyl]phenyl piperazine::CHEMBL365597

SMILES NCCC(=O)N[C@H](Cc1ccc(Cl)cc1Cl)C(=O)N1CCN(CC1)c1ccccc1CNCCc1cccs1

InChI Key InChIKey=KKBPPVVSQKSKNV-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50158484   

TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50158484(3-Amino-N-[(R)-1-(2,4-dichloro-benzyl)-2-oxo-2-(4-...)
Affinity DataKi:  1.80nMAssay Description:Agonist activity at human MC4 receptor expressed in HEK293 cells assessed as stimulation of cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50158484(3-Amino-N-[(R)-1-(2,4-dichloro-benzyl)-2-oxo-2-(4-...)
Affinity DataKi:  1.80nMAssay Description:Binding affinity for melanocortin-4 receptor transfected in HEK 293 cells using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50158484(3-Amino-N-[(R)-1-(2,4-dichloro-benzyl)-2-oxo-2-(4-...)
Affinity DataKi:  1.80nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50158484(3-Amino-N-[(R)-1-(2,4-dichloro-benzyl)-2-oxo-2-(4-...)
Affinity DataKi:  1.80nMAssay Description:Binding affinity to human MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50158484(3-Amino-N-[(R)-1-(2,4-dichloro-benzyl)-2-oxo-2-(4-...)
Affinity DataKi:  280nMAssay Description:Displacement of [125]NDP-MSH from human MC5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50158484(3-Amino-N-[(R)-1-(2,4-dichloro-benzyl)-2-oxo-2-(4-...)
Affinity DataKi:  640nMAssay Description:Displacement of [125]NDP-MSH from human MC3receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50158484(3-Amino-N-[(R)-1-(2,4-dichloro-benzyl)-2-oxo-2-(4-...)
Affinity DataKi:  640nMAssay Description:Binding affinity for melanocortin-3 receptor transfected in HEK 293 cells using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50158484(3-Amino-N-[(R)-1-(2,4-dichloro-benzyl)-2-oxo-2-(4-...)
Affinity DataKi:  4.20E+3nMAssay Description:Displacement of [125]NDP-MSH from human MC1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed