BDBM50158457 (4-hydroxyphenyl)(2-methylbenzofuran-3-yl)methanone::CHEMBL374618::US9725430, Compound 1k::US9962362, Compound 1k

SMILES Cc1oc2ccccc2c1C(=O)c1ccc(O)cc1

InChI Key InChIKey=BCQDWIKXULTIHQ-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50158457   

TargetEyes absent homolog 3(Human)
Cincinnati Childrens Hospital Medical Center

US Patent
LigandPNGBDBM50158457((4-hydroxyphenyl)(2-methylbenzofuran-3-yl)methanon...)
Affinity DataIC50: 8.11E+4nMAssay Description:An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003))....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetEyes absent homolog 3(Human)
Cincinnati Childrens Hospital Medical Center

US Patent
LigandPNGBDBM50158457((4-hydroxyphenyl)(2-methylbenzofuran-3-yl)methanon...)
Affinity DataIC50: 8.11E+4nMAssay Description:The compounds were then tested using full-length human recombinant, purified EYA3 and pNPP as a substrate. Compounds were dissolved in DMSO and dilut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
Go to US Patent

TargetCytochrome P450 2C19(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50158457((4-hydroxyphenyl)(2-methylbenzofuran-3-yl)methanon...)
Affinity DataKi:  2.50E+3nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed