BDBM50158452 CHEMBL224122::N-(3-(phenylthio)pyridin-4-yl)methanesulfonamide::N-(3-phenylsulfanyl-4-pyridinyl)methanesulfonamide

SMILES CS(=O)(=O)Nc1ccncc1Sc1ccccc1

InChI Key InChIKey=SQQJATJQZCRBEZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50158452   

TargetProstaglandin G/H synthase 1(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50158452(N-(3-(phenylthio)pyridin-4-yl)methanesulfonamide |...)
Affinity DataIC50: 3.62E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of calcium ionophore A-23187-stimulated platelet aggregation by measuring TXB2 product...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50158452(N-(3-(phenylthio)pyridin-4-yl)methanesulfonamide |...)
Affinity DataIC50: 1.19E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50158452(N-(3-(phenylthio)pyridin-4-yl)methanesulfonamide |...)
Affinity DataIC50: 3.62E+3nMAssay Description:Inhibition of COX1 in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50158452(N-(3-(phenylthio)pyridin-4-yl)methanesulfonamide |...)
Affinity DataIC50: 1.19E+3nMAssay Description:Inhibition of COX2 in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed