BDBM50158052 4-[5-Bromo-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-indole-1-sulfonyl]-phenylamine::CHEMBL178767

SMILES Nc1ccc(cc1)S(=O)(=O)n1cc(C2=CCNCC2)c2cc(Br)ccc12

InChI Key InChIKey=ZSBJHKSWXPYBKP-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50158052   

Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50158052(4-[5-Bromo-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-ind...)
Affinity DataIC50: 33.7nMAssay Description:Inhibitory concentration against 5-HT stimulated cAMP production in HeLa cells stably transfected with human 5-HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50158052(4-[5-Bromo-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-ind...)
Affinity DataKi:  7nMAssay Description:Binding affinity against cloned human 5-hydroxytryptamine 6 receptor expressed in HeLa cells using [3H]LSDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed