BDBM50158037 1-Benzyl-3-(1-methyl-1,2,3,6-tetrahydro-pyridin-4-yl)-1H-indole::CHEMBL281937

SMILES CN1CCC(=CC1)c1cn(Cc2ccccc2)c2ccccc12

InChI Key InChIKey=JCCNEBIRCTWQEL-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50158037   

Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50158037(1-Benzyl-3-(1-methyl-1,2,3,6-tetrahydro-pyridin-4-...)
Affinity DataIC50: 14.8nMAssay Description:Inhibitory concentration against 5-HT stimulated cAMP production in HeLa cells stably transfected with human 5-HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50158037(1-Benzyl-3-(1-methyl-1,2,3,6-tetrahydro-pyridin-4-...)
Affinity DataKi:  10nMAssay Description:Binding affinity against cloned human 5-hydroxytryptamine 6 receptor expressed in HeLa cells using [3H]LSDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
University of Georgia

Curated by ChEMBL
LigandPNGBDBM50158037(1-Benzyl-3-(1-methyl-1,2,3,6-tetrahydro-pyridin-4-...)
Affinity DataKi:  15nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor using [3H]-ketanserin as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Georgia

Curated by ChEMBL
LigandPNGBDBM50158037(1-Benzyl-3-(1-methyl-1,2,3,6-tetrahydro-pyridin-4-...)
Affinity DataKi:  1.00E+4nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Georgia

Curated by ChEMBL
LigandPNGBDBM50158037(1-Benzyl-3-(1-methyl-1,2,3,6-tetrahydro-pyridin-4-...)
Affinity DataKi:  1.00E+4nMAssay Description:Binding affinity of a compound to rat brain 5-hydroxytryptamine 1A (serotonin) receptor assayed by radiolabeled [3H]-8-OH-DPAT ligand displacementMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed