BDBM50158036 4-[3-(1,2,3,6-Tetrahydro-pyridin-4-yl)-indole-1-sulfonyl]-isothiazolo[4,5-c]pyridine::CHEMBL182099

SMILES O=S(=O)(c1nccc2sncc12)n1cc(C2=CCNCC2)c2ccccc12

InChI Key InChIKey=GRDKGQSOKNBODD-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50158036   

Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50158036(4-[3-(1,2,3,6-Tetrahydro-pyridin-4-yl)-indole-1-su...)
Affinity DataIC50: 169nMAssay Description:Inhibitory concentration against 5-HT stimulated cAMP production in HeLa cells stably transfected with human 5-HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50158036(4-[3-(1,2,3,6-Tetrahydro-pyridin-4-yl)-indole-1-su...)
Affinity DataKi:  5nMAssay Description:Binding affinity against cloned human 5-hydroxytryptamine 6 receptor expressed in HeLa cells using [3H]LSDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed