BDBM50158026 1-(2-Fluoro-benzenesulfonyl)-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-indole::CHEMBL180606

SMILES Fc1ccccc1S(=O)(=O)n1cc(C2=CCNCC2)c2ccccc12

InChI Key InChIKey=WIXPGFSAQJCJED-UHFFFAOYSA-N

Data  5 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50158026   

Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50158026(1-(2-Fluoro-benzenesulfonyl)-3-(1,2,3,6-tetrahydro...)
Affinity DataIC50: 2.70nMAssay Description:Inhibitory concentration against 5-HT stimulated cAMP production in HeLa cells stably transfected with human 5-HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50158026(1-(2-Fluoro-benzenesulfonyl)-3-(1,2,3,6-tetrahydro...)
Affinity DataKi:  1nMAssay Description:Binding affinity against cloned human 5-hydroxytryptamine 6 receptor expressed in HeLa cells using [3H]LSDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50158026(1-(2-Fluoro-benzenesulfonyl)-3-(1,2,3,6-tetrahydro...)
Affinity DataKi:  741nMAssay Description:Binding affinity against human cloned Dopamine receptor D3 stably expressed in CHO-K1 cells using [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50158026(1-(2-Fluoro-benzenesulfonyl)-3-(1,2,3,6-tetrahydro...)
Affinity DataKi:  875nMAssay Description:Binding affinity against human cloned 5-hydroxytryptamine 1A receptor stably expressed in CHO cells using [3H]5-HTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50158026(1-(2-Fluoro-benzenesulfonyl)-3-(1,2,3,6-tetrahydro...)
Affinity DataKi: >2.00E+3nMAssay Description:Binding affinity against human cloned Dopamine receptor D2 stably expressed in CHO-K1 cells using [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50158026(1-(2-Fluoro-benzenesulfonyl)-3-(1,2,3,6-tetrahydro...)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity against human cloned Dopamine receptor D4 stably expressed in CHO-K1 cells using [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed