BDBM50157863 CHEMBL182968::[3-Biphenyl-4-yl-2-(5-tert-butoxycarbonylamino-pentylamino)-3,4-dihydro-quinazolin-4-yl]-acetic acid methyl ester::methyl 2-(3-(biphenyl-4-yl)-2-(5-(tert-butoxycarbonylamino)pentylamino)-3,4-dihydroquinazolin-4-yl)acetate

SMILES COC(=O)CC1N(C(NCCCCCNC(=O)OC(C)(C)C)=Nc2ccccc12)c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=PDYGWPOBXZQADF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50157863   

TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50157863(methyl 2-(3-(biphenyl-4-yl)-2-(5-(tert-butoxycarbo...)
Affinity DataIC50: 679nMAssay Description:Inhibition of human T-type calcium channel alpha1G in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50157863(methyl 2-(3-(biphenyl-4-yl)-2-(5-(tert-butoxycarbo...)
Affinity DataIC50: 680nMAssay Description:Inhibition of T-type calcium channel Cav3.1 alpha1G expressed in HEK293 cells by whole cell patch-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50157863(methyl 2-(3-(biphenyl-4-yl)-2-(5-(tert-butoxycarbo...)
Affinity DataIC50: 680nMAssay Description:Inhibition of T-type [Ca2+] channel (alpha1G) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed