BDBM50157861 CHEMBL362667::tert-butyl 5-(4-(2-(benzylamino)-2-oxoethyl)-2-(biphenyl-4-ylamino)quinazolin-3(4H)-yl)pentylcarbamate::{5-[4-(Benzylcarbamoyl-methyl)-2-(biphenyl-4-ylamino)-4H-quinazolin-3-yl]-pentyl}-carbamic acid tert-butyl ester

SMILES CC(C)(C)OC(=O)NCCCCCN1C(CC(=O)NCc2ccccc2)c2ccccc2N=C1Nc1ccc(cc1)-c1ccccc1

InChI Key InChIKey=IOVUWPHJDGHLAZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50157861   

TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50157861({5-[4-(Benzylcarbamoyl-methyl)-2-(biphenyl-4-ylami...)
Affinity DataIC50: 170nMAssay Description:Inhibition of human T-type calcium channel alpha1G in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50157861({5-[4-(Benzylcarbamoyl-methyl)-2-(biphenyl-4-ylami...)
Affinity DataIC50: 170nMAssay Description:Inhibition of T-type calcium channel Cav3.1 alpha1G expressed in HEK293 cells by whole cell patch-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50157861({5-[4-(Benzylcarbamoyl-methyl)-2-(biphenyl-4-ylami...)
Affinity DataIC50: 170nMAssay Description:Inhibition of T-type [Ca2+] channel (alpha1G) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed