BDBM50157859 CHEMBL360359::[2-(5-amino-pentylamino)-3-biphenyl-4-yl-3,4-dihydro-quinazolin-4-yl]-acetic acid methyl ester::methyl 2-(2-(5-aminopentylamino)-3-(biphenyl-4-yl)-3,4-dihydroquinazolin-4-yl)acetate

SMILES COC(=O)CC1N(C(NCCCCCN)=Nc2ccccc12)c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=IAVHQTHZEBUNLX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50157859   

TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50157859(methyl 2-(2-(5-aminopentylamino)-3-(biphenyl-4-yl)...)
Affinity DataIC50: 560nMAssay Description:Inhibition of human T-type calcium channel alpha1G in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50157859(methyl 2-(2-(5-aminopentylamino)-3-(biphenyl-4-yl)...)
Affinity DataIC50: 560nMAssay Description:Inhibition of T-type calcium channel Cav3.1 expressed in HEK293 cells co-expressing alpha1G subunit by whole-cell patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50157859(methyl 2-(2-(5-aminopentylamino)-3-(biphenyl-4-yl)...)
Affinity DataIC50: 560nMAssay Description:Inhibition of T-type calcium channel Cav3.1 alpha-1G subunit expressed in HEK293 cells assessed as calcium current by patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50157859(methyl 2-(2-(5-aminopentylamino)-3-(biphenyl-4-yl)...)
Affinity DataIC50: 560nMAssay Description:Inhibition of T-type [Ca2+] channel (alpha1G) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed