BDBM50157850 3-Hydroxy-1-phenyl-1H-thieno[2,3-d]pyrimidine-2,4-dione::CHEMBL182974

SMILES On1c(=O)n(Cc2ccccc2)c2sccc2c1=O

InChI Key InChIKey=YGSHEPGNPDRIPY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50157850   

TargetDNA excision repair protein ERCC-5(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50157850(3-Hydroxy-1-phenyl-1H-thieno[2,3-d]pyrimidine-2,4-...)
Affinity DataIC50: 2nMAssay Description:Inhibitory concentration against the xeroderma pigmentosum GMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50157850(3-Hydroxy-1-phenyl-1H-thieno[2,3-d]pyrimidine-2,4-...)
Affinity DataIC50: 0.230nMAssay Description:Inhibitory concentration against the Flap endonuclease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50157850(3-Hydroxy-1-phenyl-1H-thieno[2,3-d]pyrimidine-2,4-...)
Affinity DataIC50: 680nMAssay Description:Inhibition of FEN1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2016
Entry Details Article
PubMed
TargetDeoxyribonuclease-1(Human)
Mrc Technology

Curated by ChEMBL
LigandPNGBDBM50157850(3-Hydroxy-1-phenyl-1H-thieno[2,3-d]pyrimidine-2,4-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of DNAse1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2016
Entry Details Article
PubMed