BDBM50157849 3''-(3-Hydroxy-7-methyl-2,4-dioxo-3,4-dihydro-2H-thieno[3,2-d]pyrimidin-1-ylmethyl)-biphenyl-4-carboxylic acid amide::CHEMBL181907

SMILES Cc1csc2c1n(Cc1cccc(c1)-c1ccc(cc1)C(N)=O)c(=O)n(O)c2=O

InChI Key InChIKey=QRJBSCORMUBJFG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50157849   

TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50157849(3''-(3-Hydroxy-7-methyl-2,4-dioxo-3,4-dihydro-2H-t...)
Affinity DataIC50: 1.08nMAssay Description:Inhibitory concentration against the Flap endonuclease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA excision repair protein ERCC-5(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50157849(3''-(3-Hydroxy-7-methyl-2,4-dioxo-3,4-dihydro-2H-t...)
Affinity DataIC50: 30.2nMAssay Description:Inhibitory concentration against the xeroderma pigmentosum GMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed