BDBM50157768 5-(4-(2-methoxyphenyl)piperazin-1-yl)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)pentanamide::CHEMBL222864

SMILES COc1ccccc1N1CCN(CCCCC(=O)NC2CCCc3ccccc23)CC1

InChI Key InChIKey=COFRSTRKYJRGFB-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50157768   

Target5-hydroxytryptamine receptor 7(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50157768(5-(4-(2-methoxyphenyl)piperazin-1-yl)-N-(1,2,3,4-t...)
Affinity DataKi:  6.05nMAssay Description:Displacement of [3H]LSD from rat recombinant 5HT7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50157768(5-(4-(2-methoxyphenyl)piperazin-1-yl)-N-(1,2,3,4-t...)
Affinity DataKi:  6.10nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor transfected in CFO-K1 cells after 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50157768(5-(4-(2-methoxyphenyl)piperazin-1-yl)-N-(1,2,3,4-t...)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in Wistar Han rat hippocampal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50157768(5-(4-(2-methoxyphenyl)piperazin-1-yl)-N-(1,2,3,4-t...)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]5-HT from human 5HT7 receptor transfected in CFO-K1 cells after 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2016
Entry Details Article
PubMed