BDBM50157717 CHEMBL3786581

SMILES CC1(C)CCC(C)(C)c2cc(ccc12)C1(OCCO1)c1ccc(\C=C\C(O)=O)cc1

InChI Key InChIKey=DFTYJVMZQNRUIU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50157717   

TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM50157717(CHEMBL3786581)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM50157717(CHEMBL3786581)
Affinity DataIC50: 240nMAssay Description:Inhibition of microsomal fraction of human CYP26A1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM50157717(CHEMBL3786581)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate by LC-MS/MS analysis in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed