BDBM50157709 CHEMBL3786508

SMILES C\C(=C/c1noc(Cn2cnc3ncn(C)c3c2=O)n1)c1ccc(Cl)cc1

InChI Key InChIKey=ILSIWKXOFBZDGE-UHFFFAOYSA-N

Data  4 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50157709   

LigandPNGBDBM50157709(CHEMBL3786508)
Affinity DataIC50: 71nMAssay Description:Antagonist activity at human TRPA1 expressed in tetracycline-inducible T-REx expression system transfected CHO cells assessed as inhibition of AITC-i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
LigandPNGBDBM50157709(CHEMBL3786508)
Affinity DataIC50: 75nMAssay Description:Antagonist activity at rat TRPA1 expressed in tetracycline-inducible T-REx expression system transfected CHO cells assessed as inhibition of AITC-ind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
LigandPNGBDBM50157709(CHEMBL3786508)
Affinity DataIC50: 55nMAssay Description:Antagonist activity at rat TRPA1 expressed in tetracycline-inducible T-REx expression system transfected CHO cells assessed as inhibition of AITC-ind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
LigandPNGBDBM50157709(CHEMBL3786508)
Affinity DataIC50: 63nMAssay Description:Antagonist activity at human TRPA1 expressed in tetracycline-inducible T-REx expression system transfected CHO cells assessed as inhibition of AITC-i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
LigandPNGBDBM50157709(CHEMBL3786508)
Affinity DataEC50: >4.00E+4nMAssay Description:Agonist activity at rat TRPA1 expressed in tetracycline-inducible T-REx expression system transfected CHO cells by 45Ca2+ uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
LigandPNGBDBM50157709(CHEMBL3786508)
Affinity DataEC50: >4.00E+4nMAssay Description:Agonist activity at human TRPA1 expressed in tetracycline-inducible T-REx expression system transfected CHO cells by 45Ca2+ uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed