BDBM50157606 CHEMBL3785432

SMILES CCCS(=O)(=O)c1nc(NC2CC2)cc(n1)-c1ccc2n(ccc2c1)C1CC(C)(C)NC(C)(C)C1

InChI Key InChIKey=XVECNLUKQDKOST-UHFFFAOYSA-N

Data  5 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50157606   

TargetChromatin remodeling regulator CECR2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50157606(CHEMBL3785432)
Affinity DataKd:  80nMAssay Description:Binding affinity to CERC2 (unknown origin) by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetChromatin remodeling regulator CECR2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50157606(CHEMBL3785432)
Affinity DataIC50: 47nMAssay Description:Binding affinity to CERC2 (unknown origin) by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetChromatin remodeling regulator CECR2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50157606(CHEMBL3785432)
Affinity DataKd:  79nMAssay Description:Binding affinity to CECR2 (unknown origin) by ITC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetPeregrin(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50157606(CHEMBL3785432)
Affinity DataIC50: 4.40E+3nMAssay Description:Alphascreen assay. Binding to BRPF1B (domain start/stop: M626-G740) by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetChromatin remodeling regulator CECR2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50157606(CHEMBL3785432)
Affinity DataIC50: 38nMAssay Description:Alphascreen assay. Binding to CECR2A (domain start/stop: P420-D543) by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetChromatin remodeling regulator CECR2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50157606(CHEMBL3785432)
Affinity DataIC50: 19nMAssay Description:Alphascreen assay. Binding to CECR2A (domain start/stop: P420-H538) by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetNucleosome-remodeling factor subunit BPTF(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50157606(CHEMBL3785432)
Affinity DataIC50: 1.46E+3nMAssay Description:Alphascreen assay. Binding to FALZA (domain start/stop: S2791-H2911) by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed