BDBM50157497 4-[6-hydroxy-1-(2,2,2-trifluoroethyl)-1H-indazol-3-yl]benzene-1,3-dio::CHEMBL225404

SMILES Oc1ccc(-c2nn(CC(F)(F)F)c3cc(O)ccc23)c(O)c1

InChI Key InChIKey=YUMVZGGRPJTXIJ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50157497   

TargetEstrogen receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50157497(4-[6-hydroxy-1-(2,2,2-trifluoroethyl)-1H-indazol-3...)
Affinity DataIC50: 165nMAssay Description:Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NF-kappaB transcriptionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50157497(4-[6-hydroxy-1-(2,2,2-trifluoroethyl)-1H-indazol-3...)
Affinity DataEC50:  4.79E+3nMAssay Description:Activity at human ERalpha expressed in HAECT1 cells assessed as stimulation of creatine kinase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed