BDBM50157485 4-[1-isopropyl-7-(trifluoromethyl)-1H-indazol-3-yl]phenol::CHEMBL386502

SMILES CC(C)n1nc(-c2ccc(O)cc2)c2cccc(c12)C(F)(F)F

InChI Key InChIKey=GOVUQMINVPOQRS-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50157485   

TargetEstrogen receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50157485(4-[1-isopropyl-7-(trifluoromethyl)-1H-indazol-3-yl...)
Affinity DataIC50: 3nMAssay Description:Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NF-kappaB transcriptionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50157485(4-[1-isopropyl-7-(trifluoromethyl)-1H-indazol-3-yl...)
Affinity DataEC50:  11nMAssay Description:Activity at human ERalpha expressed in HAECT1 cells assessed as stimulation of creatine kinase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed