BDBM50157367 CHEMBL183506::N-((R)-1-{4-[4-(2-Methoxy-phenylsulfanyl)-3-trifluoromethyl-phenyl]-pyridin-2-yl}-pyrrolidin-3-yl)-acetamide

SMILES COc1ccccc1Sc1ccc(cc1C(F)(F)F)-c1ccnc(c1)N1CC[C@H](C1)NC(C)=O

InChI Key InChIKey=ZBALKPBJFFDXAB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50157367   

TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50157367(N-((R)-1-{4-[4-(2-Methoxy-phenylsulfanyl)-3-triflu...)
Affinity DataIC50: 88nMAssay Description:Inhibitory concentration against integrin LFA-1/ICAM-1 binding complexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed